Βρήκα αυτό: http://www.windowsdevcenter.com/pub/a/windows/2005/02/08/NTFS_Hacks.html
3. Use More Folders
If you frequently need to open, close, create, or delete certain types of files, keep the number of such files in each folder small. In other words, if you have a lot of these files, create additional folders to spread them out between folders. If this isn't practical for some reason, then the first two hacks above can help compensate for having too many files in one folder.
4. Use More Partitions
In Windows 2000, when you partition a large disk (50GB or more, say) into several smaller NTFS volumes (10GB each), you can speed disk performance by up to 10 percent. NTFS on Windows XP has been improved to perform better overall, but you can still squeeze a percent or two of better performance out of a large disk by partitioning it into several smaller volumes.
Έχει και άλλα tips μέσα, ρίξε μια ματιά ίσως κάποια βοηθήσουν
Χρήστος Γεωργακόπουλος